Index of Previous Articles

Screening for hepatitis C in high-risk patients Sept 2006 Infection with hepatitis C virus (HCV) is the most common blood-borne infection in the United States and the leading cause of death from liver disease.1-3 Although treatment has improved greatly over the past 5 years with the use of antiviral combination therapy (peginterferon plus ribavirin), diagnosis remains elusive and inconsistent in the absence of HCV-specific blood screening.	Symposium: When PSA levels rise after prostatectomy Sept 2006 Twenty to thirty percent of men experience a rising PSA level after radical prostatectomy for prostate cancer, and much controversy exists about how best to manage these patients. In this symposium, an outstanding panel of experts discusses various approaches for different clinical scenarios involving this diverse population of men.
Muraglitazar: A dual peroxisome proliferator-activated receptor agonist Sept 2006 Muraglitazar is a new agent under investigation for the treatment of patients with type 2 diabetes. It belongs to a novel class of drugs that target the peroxisome proliferator-activated receptors, both alpha and gamma subtypes. Available clinical data describe improvements in glycemic parameters similar to available thiazolidinediones. Safety data are limited, but in available abstracts, there are reports of moderately elevated rates of edema, weight gain, and hypoglycemia with muraglitazar compared with placebo or pioglitazone.	Aspirin resistance: a growing concern Oct 2006 Aspirin is the cornerstone of therapy in the treatment and prevention of cardiovascular disease. The potential benefit of aspirin therapy may be significantly reduced in patients with aspirin resistance, creating a clinical and economic burden on the healthcare system. The purpose of this article is to clarify the term "aspirin resistance," describe the proposed mechanisms, review the clinical outcome studies with associated resistance testing, and discuss the potential pharmacologic management of this problem.
Treatment of heart failure with reduced left ventricular ejection fraction Oct 2006 Heart failure (HF) affects approximately 5 million persons in the United States each year. HF is predominantly a disease of the elderly: Approximately 80% of patients hospitalized with HF are older than age 65. Approximately one-half of older adult patients with CHF have a decreased ejection fraction. Elderly patients with HF and a reduced LVEF have a higher mortality than elderly patients with HF with a normal LVEF.	HIV/AIDS in older adults: A case report and literature review Oct 2006 Infection with the human immunodeficiency virus (HIV) and its result acquired immunodeficiency syndrome (AIDS) is a worldwide problem affecting individuals of all ages and backgrounds. More than 10% of HIV infection is found in adults age 50 and older; it is difficult to determine rates of HIV infection among older adults, however, because few people over age 50 at risk for HIV routinely get tested.
Exubera An Orally inhaled insulin Nov 2006 Long-term glycemic control substantially reduces the risk of diabetes mellitus-related complications. Insulin is a mainstay in therapy in type 1 and later-stage type 2 diabetes mellitus. Although insulin is effective in controlling blood glucose and hemoglobin A1c concentrations, the need for subcutaneous injection can be a burden for patients, which can impact compliance.	What you can do to prevent cervical cancer and other HPV-related diseases Nov 2006 Vaccines show great promise for primary prevention of human papillomavirus infection, but effective screening, using the latest guidelines, and education are still key. As a pediatrician, you will play an increasingly important role in protecting your adolescent patients from HPV-related disease
Update on the approaches to pancreatic disease Nov 2006 Acute pancreatitis is potentially life threatening and requires prompt diagnosis, effective pain management, and careful monitoring. Recognizing chronic pancreatitis can be difficult, and a delayed diagnosis can allow the development of diabetes, severe pain, and pseudocysts. Pancreatic cancer is a highly lethal malignancy that requires prompt diagnosis. For most patients, balancing the choice of treatment with quality-of-life issues is critical, since no curative therapy exists.	Is an MBA worth it? Nov 2006 More and more physicians are getting MBAs. But are there any real benefits to adding that degree to your name? When Michael Genovesi, a critical care pulmonologist in New Britain, CT, decided in the mid-'90s to go back to school after 20 years in practice, it wasn't to learn about the fall of the Roman Empire or Giotto's early frescoes. It was to study business in the University of Connecticut's Executive MBA program.
A clinician's guide to safe and effective tick removal Nov 2006 The discovery of an attached tick on a child can provoke great anxiety in parents. Here are concise instructions for completely removing those tiny, stubborn subjects of worrisome scrutiny in your office. Includes a Guide for Parents.	Medical Errors: Living with your mistakes Dec 2006 The stiff-upper-lip approach to dealing with medical errors doesn't help your practice, your patients, or you. Mistakes—even those for which you aren't directly responsible—often result in self-recrimination, second-guessing, and extended periods of simply feeling awful.
Hand-assisted laparoscopy: Advances and advantages Dec 2006 Hand-assisted laparoscopy combines the finest aspects of open surgery with those of laparoscopy. Insertion of the non-dominant hand into the operative field enables surgeons to overcome many obstacles associated with conventional laparoscopy?including loss of proprioception, tactile sensation, and spatial orientation?while also decreasing the learning curve. As this technique grows in popularity, its scope of use has expanded to include more complex indications.	Lactic acidosis associated with metformin use in treatment of type 2 diabetes mellitus Jan 2007 Metformin, an antihyperglycemic, is widely used in the treatment of type 2 diabetes mellitus (DM). A rare, but important complication associated with this drug is the development of lactic acidosis: Overall mortality of lactic acidosis is approximately 50%. Certain subsets of patients taking metformin are at greater risk of developing lactic acidosis.
Should we screen for Alzheimer's disease? Jan. 2007 Fewer than one-half of all Alzheimer's disease (AD) patients are currently diagnosed; approximately 25% are treated with antidementia compounds. An emerging consensus suggest that the three keys to the successful treatment of Alzheimer's disease are early detection, use of currently approved medications to provide symptomatic treatment, and development of medications to slow and eventually halt disease progression.	The latest in cutaneous ulcer care Jan 2007 For all the many types and causes of these common problem wounds, there are many more therapeutic options. What caused the ulcer is key to the treatment, and a multidisciplinary approach is often the best course.
Exploring role of elective lymph node dissection in managing high-risk CSCC The jury is still out on whether patients with high-risk cutaneous squamous cell carcinoma (CSCC) whose lymph nodes are clinically node-negative (N0) may benefit from elective neck dissection (END), according to Jonathan L. Cook, M.D., associate professor of medicine and director of dermatologic surgery, Duke University Medical Center, Durham, N.C. END, a diagnostic staging procedure, allows microscopic detection of subclinical nodal metastases.	Screening for hepatitis C in high-risk patients Infection with hepatitis C virus (HCV) is the most common blood-borne infection in the United States and the leading cause of death from liver disease.1-3 Although treatment has improved greatly over the past 5 years with the use of antiviral combination therapy (peginterferon plus ribavirin), diagnosis remains elusive and inconsistent in the absence of HCV-specific blood screening.
Symposium: When PSA levels rise after prostatectomy Twenty to thirty percent of men experience a rising PSA level after radical prostatectomy for prostate cancer, and much controversy exists about how best to manage these patients. In this symposium, an outstanding panel of experts discusses various approaches for different clinical scenarios involving this diverse population of men.	How effective is pharmacotherapy for overactive bladder? As defined at a recent International Continence Society (ICS) meeting, overactive bladder (OAB) syndrome encompasses disturbance of bladder function that leads to urgency, with or without urge incontinence, and voiding frequency, including nocturia. This review on the pharmacologic therapies available for OAB syndrome is organized around this definition, which includes a symptom complex thought to be primarily of bladder origin (urgency and voiding frequency) with or without a secondary sign (urge incontinence) typically related to the interaction of the bladder and surrounding structures of the pelvis (nerves and pelvic floor muscles).
Muraglitazar: A dual peroxisome proliferator-activated receptor agonist Muraglitazar is a new agent under investigation for the treatment of patients with type 2 diabetes. It belongs to a novel class of drugs that target the peroxisome proliferator-activated receptors, both alpha and gamma subtypes. Available clinical data describe improvements in glycemic parameters similar to available thiazolidinediones. Safety data are limited, but in available abstracts, there are reports of moderately elevated rates of edema, weight gain, and hypoglycemia with muraglitazar compared with placebo or pioglitazone.	Exubera An Orally inhaled insulin Long-term glycemic control substantially reduces the risk of diabetes mellitus-related complications. Insulin is a mainstay in therapy in type 1 and later-stage type 2 diabetes mellitus. Although insulin is effective in controlling blood glucose and hemoglobin A1c concentrations, the need for subcutaneous injection can be a burden for patients, which can impact compliance. Exubera is an inhaled insulin that has demonstrated results similar to conventional short-acting insulin products while also increasing overall patient satisfaction.
What you can do to prevent cervical cancer and other HPV-related diseases May 2007 Vaccines show great promise for primary prevention of human papillomavirus infection, but effective screening, using the latest guidelines, and education are still key. As a pediatrician, you will play an increasingly important role in protecting your adolescent patients from HPV-related disease.	Update on the approaches to pancreatic disease May 2007 Acute pancreatitis is potentially life threatening and requires prompt diagnosis, effective pain management, and careful monitoring. Recognizing chronic pancreatitis can be difficult, and a delayed diagnosis can allow the development of diabetes, severe pain, and pseudocysts. Pancreatic cancer is a highly lethal malignancy that requires prompt diagnosis. For most patients, balancing the choice of treatment with quality-of-life issues is critical, since no curative therapy exists.
A call to join the fight against bacterial resistance The emergence of pathogens that are resistant to first-line antibiotics has made managing common bacterial infections more complex. The authors guide you to help minimize resistance.	A clinician's guide to safe and effective tick removal June 2007 The discovery of an attached tick on a child can provoke great anxiety in parents. Here are concise instructions for completely removing those tiny, stubborn subjects of worrisome scrutiny in your office. Includes a Guide for Parents..
Cancer Support Services: Hotline and Web Site The AstraZeneca Cancer Support Network (AZ CSN) provides comprehensive, up-to-date medical and reimbursement information for AstraZeneca oncology products. The AZ CSN is available to patients and health care professionals.	HIV/AIDS in older adults: A case report and literature review Infection with the human immunodeficiency virus (HIV) and its result acquired immunodeficiency syndrome (AIDS) is a worldwide problem affecting individuals of all ages and backgrounds. More than 10% of HIV infection is found in adults age 50 and older; it is difficult to determine rates of HIV infection among older adults, however, because few people over age 50 at risk for HIV routinely get tested.
Treatment of heart failure with reduced left ventricular ejection fraction Heart failure (HF) affects approximately 5 million persons in the United States each year. HF is predominantly a disease of the elderly: Approximately 80% of patients hospitalized with HF are older than age 65. Approximately one-half of older adult patients with CHF have a decreased ejection fraction. Elderly patients with HF and a reduced LVEF have a higher mortality than elderly patients with HF with a normal LVEF.	HIV/AIDS in older adults: A case report and literature review Jan. 2008 Infection with the human immunodeficiency virus (HIV) and its result acquired immunodeficiency syndrome (AIDS) is a worldwide problem affecting individuals of all ages and backgrounds. More than 10% of HIV infection is found in adults age 50 and older; it is difficult to determine rates of HIV infection among older adults, however, because few people over age 50 at risk for HIV routinely get tested.
Adding A Disk Drive Updated 9/15/2006	Air Force Study Suggests Agent Orange, Diabetes Link
Advances in PC Hardware	ALLHAT
Advertising on the Internet 8/9/99	Aging Part 1.
Affiliate Programs Updated 8/1/2003	Aging part 2.
Backing Up Your Computer Updated 10/04	Aging part 3.
Communicating Computer to Computer	Anger Management in Children
A Computer for the Next Few Years	Anger Management
Configuring the Windows 95 Dialer	Carbon Monoxide Poisoning
Designing A Web Site	Common Sense and Cholesterol
Doing Business on the Internet	Conventional Versus Complementary Eye Care
Domain Names	Copper and Iodine
E-mail addresses	Coq10
E-mail and Span	Developing New Products for Patent
E-mail Gone Crazy 6/12/99	Exercise
Flat Panel Displays Now Available Updated 10/04	Fats
Procrastination	Gulf War Veterans Sought
Fourth-Generation Browsers	Healthcare and the Elderly
Graphics Boards	Lupus or SLE
Help with Search Engines 3/10/99	Knowing How to Manage Problems
Internet Hoaxes	Please Define Excessive
Internet Connection Options	PHO's
Internet Access Revisited	Positive Self Image
Introduction to Healthcare on the Internet	Raising the Standards of the Fitness Industry
How Cache Makes Browsing Faster	Stress Management
Managing Your Bookmark File	Treating Gulf War Illness
Securing Your Computer	Web-enabling Health Care Transactions
On the Seminar Circuit	Endometrial Ablation - The Second Generation
Should Spam Be Outlawed?	A Breakthrough Procedure for Uterine Fibroids
Techo-Babble Defined 4/10/00	Don’t be the next victim
The need for speed Updated 4/3/02003	Foundational Anti-Aging Concepts
What's a Plug-in?	Sodium
What's new with Computers Updated 7/1/2003	Nineteen Foods to Help Prevent Breast Cancer
All that Jazz - Spam	Negotiating Claims
Y2K Doom	There's nothing wrong with me!
Your Computers Memory	How to Optimize your Antioxidents
Fraud- Phishing	Have you been denied Health Insurance because of Uterine Fibroids?
	Do You Know?

Glossary of Web Words

“Talking the talk” is critical to increasing productivity and decreasing frustration when you're working on the Internet. This is a list of web words from previous issues.